A Case of Desmoplastic Malignant Melanoma

DOI 19 References

Bibliographic Information

Other Title
  • Ｄｅｓｍｏｐｌａｓｔｉｃ　Ｍａｌｉｇｎａｎｔ　Ｍｅｌａｎｏｍａの１例

Abstract

A 71-year-old man presented with a 3-year history of a nodule on the right palm. The lesion was an elevated erosive reddish nodule with a peripheral brownish pigmented macule, measuring 10 mm in diameter, mimicking granuloma pyogenicum. Excisional resection was performed and histopathological findings showed that the tumor was filled with spindle-shaped atypical cells in the dermis with melanin deposits in some parts. A pathological diagnosis of desmoplastic malignant melanoma was established by immunohistochemical findings that showed S-100(+), HMB-45(-), vimentin(+), cytokeratin(-), α-SMA(-), NSE(-). Chest X-P and computed tomography of the head, neck and chest revealed no evidence of metastasis to the lymph nodes or other organs. Classification of Stage II C (pT4b, N0, M0, tumor thickness 12 mm, with ulceration,UICC 2002) was assigned. Additional extensive resection and immunotherapy with interferon-β were performed. There has been no sign of recurrence or metastases in 10 months since surgery.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 70 (2), 153-158, 2008

    Western Division of Japanese Dermatological Association

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Details 詳細情報について

  • CRID
    1390282679277211520
  • NII Article ID
    130004475227
  • DOI
    10.2336/nishinihonhifu.70.153
  • ISSN
    18804047
    03869784
  • Text Lang
    ja
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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