A Case of Primitive Neuroectodermal Tumor Detected by Suddenly Appeared Subepidermal Nodules.

  • NAKAGOMI Tsuneaki
    Department of Dermatology, Tokyo Kosei Nenkin Hospital
  • NANKO Hiroko
    Department of Dermatology, Tokyo Kosei Nenkin Hospital
  • MIZOO Akira
    Department of Internal Medicine, Tokyo Kosei Nenkin Hospital
  • INOUE Yasushi
    Department of Pathology, Tokyo Kosei Nenkin Hospital
  • PARK Yoyun
    Department of Hospital Pathology, Faculty of Medicine, Teikyo University

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  • 突然皮下結節として出現したPrimitive Neuroectodermal Tumor

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Primitive neuroectodermal tumor (PNET) is very rare and is classified as a type of small cell sarcoma, which includes Ewing’s sarcoma, neuroblastoma, etc.. Recently we experienced a case of PNET which was detected after a sudden appearance of subepidermal nodules. This is the second case of PNET reported by dermatologists in Japan. In our case, the tumor originally occurred in the intrapelvic space, and then invaded the soft tissue of the thigh and thereafter moved to the subepidermal tissue of the abdomen, the mesothelium of chest as well as the paraaortic and superficial lymph nodes. Unfortunately the name “PNET” is not so well known among dermatologists. But in accordance with advances in histopathological research, we expect that the reported cases of this sarcoma may increase in number in the future. We discuss this entity in general and also comment on the differential diagnosis.

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