A Case of Epithelioid Angiosarcoma Arising on the Right Waist and Hip

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  • ISHIDA Noriko
    Department of Dermatology, National Hospital Organization Kyushu Medical Center
  • MATSUDA Tomoyo
    Department of Dermatology, National Hospital Organization Kyushu Medical Center
  • TAKAMATSU Hiroko
    Department of Dermatology, National Hospital Organization Kyushu Medical Center
  • HARADA Kayo
    Department of Dermatology, National Hospital Organization Kyushu Medical Center
  • URABE Kazunori
    Department of Dermatology, National Hospital Organization Kyushu Medical Center
  • FURUE Masutaka
    Department of Dermatology, Graduate School of Medical Sciences, Kyushu University

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Other Title
  • 腰臀部に生じた Epithelioid Angiosarcoma の1 例
  • 症例 腰臀部に生じたEpithelioid Angiosarcomaの1例
  • ショウレイ ヨウデンブ ニ ショウジタ Epithelioid Angiosarcoma ノ 1レイ

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Description

A 79-year-old man was referred to our clinic complaining of multiple dark-brown painful nodules on the right waist and hip. Four months prior to visiting our clinic, he experienced a severe trauma on this site due to falling after losing consciousness. A biopsy specimen revealed a diffuse proliferation of atypical epithelioid cells with a slit-like appearance and extravasation of red blood cells. On immunohistology, the atypical tumor cells were strongly positive for CD31 and vimentin as well as AE1/AE3 and CAM5.2, leading to a diagnosis of epithelioid angiosarcoma. Investigation by positron emission tomography-computed tomography revealed osteolytic metastatic lesions in the pubic and ischial bones. Palliative radio-chemotherapy was performed, but he passed away 11 months after the first visit. Epithelioid angiosarcoma is a rare tumor,and in this case we needed to differentiate it from the metastatic lesions of a primary malignant epithelial tumor.

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