A Case of Giant Infantile Hemangioma Successfully Treated with Propranolol

TODA Sayuri, TANAKA Maiko, KAWAI Mikio, HIDE Michihiro, KARAKAWA Syuhei, AOKI Megumi, MIYAMOTO Yoshihiro

doi:10.2336/nishinihonhifu.74.394

A 10-month-old girl presented with an erythema on the left side of her face, present since 1 month of age. Despite previous treatments with dye laser surgery and intralesional injection of corticosteroids, the lesion had gradually protruded into an erythematous bulky mass with a deformity of the left auricle and difficulty in opening her left eyelid. She was diagnosed as infantile hemangioma (IH) and started on a treatment with propranolol. Propranolol was initiated at a dose of 0.25 mg/kg per day and titrated upward to 1.0 mg/kg per day. The hemangioma began to withdraw within a week, and afterward, the mass decreased without any side effects. A first line treatment of IH with a giant mass or functional disorder is currently the administration of oral or intralesional corticosteroids, but that may not be effective in some cases. Recently, the efficacy of propranolol for IH has been reported in many cases. Propranolol may be tried for the treatment of IH for extensive periods of time with an adequate monitoring of adverse effects.

A Case of Giant Infantile Hemangioma Successfully Treated with Propranolol

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