A Case of Lung Metastasis Developing 22 Years after Initial Treatment of Malignant Melanoma on the Right Neck

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  • OOKUBO Yumi
    Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences
  • OGAWA Fumihide
    Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences
  • KOIKE Yuta
    Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences
  • TOMITA Hajime
    Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences
  • OKAZAKI Shihoko
    Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences
  • KUWATSUKA Yutaka
    Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences
  • UTANI Atsushi
    Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences
  • SATO Shinichi
    Department of Dermatology, Faculty of Medicine, University of Tokyo
  • OKAZAKI Hiroshi
    Department of Thoracic Oncology, National Kyusyu Cancer Center

Bibliographic Information

Other Title
  • 22年後に肺転移を認めたUltra Late Recurrence右頚部悪性黒色腫の1例
  • 症例 22年後に肺転移を認めたUltra Late Recurrence右頚部悪性黒色腫の1例
  • ショウレイ 22ネンゴ ニ ハイ テンイ オ ミトメタ Ultra Late Recurrence ミギ ケイブ アクセイ コクショク シュ ノ 1レイ

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Abstract

We report a case of malignant melanoma of the right neck with lung metastasis, which was found 22 years after the primary lesion excision, lymph node dissection, and adjuvant therapy. A 47-year-old woman was given a diagnosis of malignant melanoma of the right neck in 1987, and underwent surgical excision and cervical lymph node dissection, as well as OK432 local administration. The tumor had a Breslow tumor thickness of 0.6 mm and was identified as pT1aN0M0, Stage IA. Since no local recurrence or metastasis were observed after a year, she stopped periodic follow-up examinations. Twenty-two years after the initial treatment, an abnormal shadow was detected by chest X-ray and PET/CT revealed a nodule at the posterior segment of the right lung (S2). A right superior lobe resection and mediastinal lymph node dissection were performed. Metastatic malignant melanoma of the lung and lymph node metastases were diagnosed by histological examination. No recurrence or metastasis have been found after 6 courses of DAC-Tam therapy. Because malignant melanoma can metastasize even after 22 years, it is necessary to carefully monitor patients with malignant melanoma.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 74 (2), 137-141, 2012

    Western Division of Japanese Dermatological Association

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