A Case of Primary Dermal Melanoma

DOI Web Site 6 References
  • YONEKURA Naomi
    Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University
  • KOBA Shinichi
    Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University
  • SHINODA Yosuke
    Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University
  • MISAGO Noriyuki
    Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University
  • NARISAWA Yutaka
    Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University
  • SUZUKI Kumiko
    Department of Otolaryngology, Head and Neck Surgery, Saga University, Faculty of Medicine, Saga University
  • KURATOMI Yuichiro
    Department of Otolaryngology, Head and Neck Surgery, Saga University, Faculty of Medicine, Saga University

Bibliographic Information

Other Title
  • Primary Dermal Melanoma の1例
  • 症例 Primary Dermal Melanomaの1例
  • ショウレイ Primary Dermal Melanoma ノ 1レイ

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Abstract

A 52-year-old man noticed a subcutaneous nodule on his left neck and the nodule was excised. Histopathological examination revealed that the tumor had been situated in the deeper dermis to subcutaneous tissue, and there were large and small cells with atypical nuclei in solid growth. On immunohistochemical examination, the tumor cells were positive for Melan-A, and HMB-45. We predicted that the tumor was metastatic melanoma. However physical examination revealed no lesion that suggested primary melanoma, and various imaging examinations revealed no metastatic lesion. We diagnosed this case as primary dermal melanoma (PDM). PDM has recently been described as a truly new variant of melanoma that is confined to the dermis and/or subcutis and histologically simulates a cutaneous metastasis. Moreover, most PDM patients have a better survival rate. In our case, we performed an expanding resection and lymph node dissection of the neck with subsequent postoperative chemotherapy. There has been no recurrence or metastasis for 54 months following the operation.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 74 (2), 146-148, 2012

    Western Division of Japanese Dermatological Association

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