A Case of Granuloma Annulare Successfully Treated with Narrow-band UVB
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- MATSUKI Shingo
- Department of Dermatology, Shimane University Faculty of Medicine
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- MIZUMOTO Kazuo
- Department of Dermatology, Matsue City Hospital
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- KAWASAKI Youji
- Department of Dermatology, Matsue City Hospital
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- YOSHIDA Manabu
- Department of Laboratory Examination, Matsue City Hospital
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- MORITA Eishin
- Department of Dermatology, Shimane University Faculty of Medicine
Bibliographic Information
- Other Title
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- 外来治療の Narrow-band UVB 療法が奏効した汎発性環状肉芽腫の1例
- 症例 外来治療のNarrow-band UVB療法が奏効した汎発性環状肉芽腫の1例
- ショウレイ ガイライ チリョウ ノ Narrow-band UVB リョウホウ ガ ソウコウ シタ ハンハツセイ カンジョウ ニクガシュ ノ 1レイ
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Abstract
A 75-year-old man with a history of type 2 diabetes mellitus (DM) presented with erythematous papules on his back and the dorsum of the hand. Skin biopsy was performed for the papules on his back, and a pathological examination showed small non-caseating epithelioid granulomas. Because no other organ abnormalities were found on a computed tomography scan and other examinations, the patient was diagnosed with cutaneous sarcoidosis. Oral corticosteroid therapy was initiated when facial papules began to appear. With the corticosteroid therapy, the facial papules almost disappeared, but type 2 DM gradually worsened. Furthermore, new annular eruptions began to appear on his abdominal area. Skin biopsy was performed for the abdominal lesions, and a pathological examination showed epithelioid granulomas with unclear margins. Based on this pathological finding and the clinical history, we diagnosed these new eruptions as granuloma annulare (GA). The annular eruptions expanded to the whole body when we decreased the amount of oral corticosteroids in order to better control DM. Narrow-band UVB therapy was initiated twice a week. When the accumulating total UVB reached 20 J/cm2,the lesions almost disappeared. Here we report the effectiveness of narrow-band UVB irradiation therapy for disseminated GA, which we could use as an outpatient treatment. Furthermore, we discuss the mechanisms of narrow-band UVB for GA treatment and the relationship between DM ingravescence and worsening GA symptoms.
Journal
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- Nishi Nihon Hifuka
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Nishi Nihon Hifuka 76 (5), 447-453, 2014
Western Division of Japanese Dermatological Association
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Keywords
Details 詳細情報について
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- CRID
- 1390282679279029248
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- NII Article ID
- 130004831881
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- NII Book ID
- AN00183881
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- ISSN
- 18804047
- 03869784
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- NDL BIB ID
- 025842694
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed
