A Case of Purpuric Drug Eruption Induced by Acetaminophen

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  • アセトアミノフェンによる紫斑型薬疹の 1 例
  • 症例 アセトアミノフェンによる紫斑型薬疹の1例
  • ショウレイ アセトアミノフェン ニ ヨル シハンガタヤクシン ノ 1レイ

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Abstract

A 15-year-old female with symptoms of a common cold and high fever developed generalized purpuric eruptions, 72 hours after internal use of several drugs in October and January, 2012-2013. A histological examination showed leukocytoclastic vasculitis. An oral challenge test with 100 mg of the suspected allergen, acetaminophen, provoked a flare up of the purpuric eruptions on the face, trunk and extremities. A drug-induced lymphocyte stimulation test (DLST) with acetaminophen was negative. We diagnosed her illness as purpuric drug eruption induced by acetaminophen.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 75 (5), 444-447, 2013

    Western Division of Japanese Dermatological Association

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