Biotransformation of monofluorophenols by cultured cells of Eucalyptus perriniana

  • Kondo Yoko
    Department of Applied Science, Okayama University of Science
  • Shimoda Kei
    Department of Pharmacology and Therapeutics, Faculty of Medicine, Oita University
  • Kubota Naoji
    Department of Pharmacology and Therapeutics, Faculty of Medicine, Oita University
  • Hamada Hatsuyuki
    National Institute of Fitness and Sports in Kanoya
  • Hamada Hiroki
    Department of Life Science, Okayama University of Science

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On the biotransformation of phenol and monofluorophenols by the cultured cells of Eucalyptus perriniana, phenyl and fluorophenyl β-D-glucosides were isolated after a 1-h incubation. Especially, the yield of 2-fluorophenol is higher than those of the other substrates, i.e., phenol, 3- and 4-fluorophenols. These results indicated that E. perriniana cells selectively glycosylate the hydroxyl group of 2-fluorophenol discriminating phenol, 3-and 4-fluorophenols.

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