両側鼻副鼻腔に多発した鼻副鼻腔髄外性形質細胞腫例

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  • A Case of Multiple Extramedullary Plasmacytomas Arising on Both Sides of the Nasal Cavity and Paranasal Sinuses
  • リョウガワ ビ フクビコウ ニ タハツ シタ ハナ フクビコウズイガイセイ ケイシツ サイボウ シュレイ

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<p>Extramedullary plasmacytomas are rare plasma cell tumors that occur mainly in the head and neck region. We report a case of multiple extramedullary plasmacytomas arising on both sides of the nasal cavity and paranasal sinuses. A 78-year-old man with a history of left cheek pain was referred to our department. The physical findings revealed a reddish brown mass in the left nasal cavity. Computed tomography and magnetic resonance imaging revealed masses on both sides of the nasal cavity and paranasal sinuses, extending into the left orbital fossa and invading the left maxillary sinus. A nasal biopsy was performed, and the tumors were pathologically diagnosed as extramedullary plasmacytomas. The patient underwent CyborD chemotherapy (a combination therapy consisting of bortezomib, dexamethasone, and cyclophosphamide) as well as radiation therapy (46 Gy) to control the tumors. The tumors disappeared rapidly, and the treatment was considered to have been effective. No recurrences have occurred to date.</p>

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