川崎医科大学耳鼻咽喉科におけるアレルギー性鼻炎の現況（第8報）―15年間の検討―

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  • Examination of Allergen Specific IgE Antibodies Using CAP-RAST between 2000 and 2014
  • カワサキ イカ ダイガク ジビ インコウカ ニ オケル アレルギーセイ ビエン ノ ゲンキョウ(ダイ8ホウ)15ネンカン ノ ケントウ

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<p>Allergic diseases, including pollinosis, have become a global public health issue. In Japan, the number of patients with allergic rhinitis has been increasing annually. According to practice guidelines for the management of allergic rhinitis in Japan, the prevalence of allergic rhinitis has increased by 10%, compared with ten years previously. In the present study, we examined 2276 patients (1206 men and 1070 women) between the ages of 1 and 85 years using the CAP-radioallergosorbent test with serum specific IgE antibodies at the Kawasaki Medical School’s Department of Otolaryngology between 2000 and 2014. The sensitization rates were as follows: cedar pollen, 58.1%; house dust mites, 47.6%; cypress pollen, 38.8%; and Dactylis glomerata, 29.8%. For house dust mites, cedar pollen, cypress pollen, and Dactylis glomerata, the percent positivity was highest in the group that was less than 20 years old, and the percent positivity decreased for older age groups. Thus, the incidence of allergy rhinitis has increased not only in adults, but also in children. For patients with allergic rhinitis, further investigation of the causative antigen is needed for treatment and diagnosis. Further epidemiological studies in various geographical regions are needed to clarify regional variations in the prevalence of allergy rhinitis.</p>

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