パクリタキセルが有効であった頭部血管肉腫の１例

DOI 被引用文献3件 参考文献7件

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  • Pacritaxel for the treatment of a patient with angiosarcoma of the scalp

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We reported a case of angiosarcoma in a 68-year-old man. The patient had noticed some subcutaneous nodules on the left side of his forehead during the previous two years. Although, he was treated first with radiotherapy and IL-2 therapy, metastasis to the left cervical lymph node and the lungs were developed one year later. For the treatment of the metastasis, we performed intravenous Pacritaxel injection concurrent with radiation and local injection of IL-2. Pacritaxel 55mg/m2 was administrated 3 times at six-day intervals. After 2 courses of this therapy, metastasis of lung resions had disappeared, leaving the side effect of leukopenia. After two courses of this treatment, we have continued the chemotherapy with a smaller dosage. Unfortunately, at the present time of 20 months after his first visit, metastasis to the abdominal wall was revealed and an aggravation tendency could not be prevented, although, the primary lesion had been kept in good condition without erosion or nodules. Pacritaxel should be recommended as an alternative treatment for angiosarcoma of the scalp. [Skin Cancer (Japan) 2004; 19: 107-111]

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