Lymphangiosarcoma in primary lymphedema of the upper limb

DOI 20 References
  • KUWABARA Shinji
    <i>Department of Dermatology, Kitasato University, School of Medicine</i>
  • NAKAHARA Chihoko
    <i>Department of Dermatology, Kitasato University, School of Medicine</i>
  • MASUZAWA Mikio
    <i>Department of Dermatology, Kitasato University, School of Medicine</i>
  • ETOH Hiromitsu
    <i>Department of Dermatology, Kitasato University, School of Medicine</i>
  • KATSUOKA Kensei
    <i>Department of Dermatology, Kitasato University, School of Medicine</i>
  • HAYAKAWA Kazushige
    <i>Radiology, Kitasato University, School of Medicine</i>
  • IWASAKI Junya
    <i>Department of Dermatology, National Defense Medical College</i>

Bibliographic Information

Other Title
  • 原発性リンパ浮腫に生じたリンパ管肉腫

Search this article

Description

A 66-year-old woman was referred to our clinic for further evaluation of lymphangiosarcoma in the right upper limb which was affected by primary, non-hereditary lymphedema at the age of 20 years. The tumor appeared five months before. She was diagnosed as having Stewart-Treves syndrome. The patient did not agree to undergo amputation of the affected arm. Intra-venous chemotherapy with paclitaxel (PTX) was performed, but caused severe bone-marrow suppression. Intra-arterial infusion of PTX was carried out to reduce blood side effects, but induced Grade 3 peripheral neural damage. The chemo drug was changed to docetaxel (DTX), combined with radiotherapy. However necrotic erythema due to DTX occurred in the upper arm. Chemotherapy was switched to oral administration of etoposide and prednisolone. Recently metastasis in the right subaxillary lymph nodes was treated by X-ray radiation. The patient has survived for a period of nineteen months without distal metastasis. This case has survived quite a long time without amputation compared with other reported cases.[Skin Cancer (Japan) 2010 ; 25 : 132-136]

Journal

  • Skin Cancer

    Skin Cancer 25 (2), 132-136, 2010

    The Japanese Skin Cancer Society

References(20)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top