A case of giant dermatofibrosarcoma protuberans with fibrosarcomatous change

DOI 4 References
  • TAKAHASHI Masayuki
    <i>Department of Dermatology, Fujita Health University School of Medicine</i>
  • IWATA Yohei
    <i>Department of Dermatology, Fujita Health University School of Medicine</i>
  • ARIMA Masaru
    <i>Department of Dermatology, Fujita Health University School of Medicine</i>
  • ABE Masamichi
    <i>Department of Dermatology, Fujita Health University School of Medicine</i>
  • SASAKI Ryosuke
    <i>Department of Dermatology, Fujita Health University School of Medicine</i>
  • TSURUTA Kyoko
    <i>Department of Dermatology, Fujita Health University Banbuntane Hotokukai Hospital</i>
  • HISAOKA Masanori
    <i>Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health</i>
  • KURODA Makoto
    <i>Department of Diagnostic Pathology, Fujita Health University School of Medicine</i>
  • MATSUNAGA Kayoko
    <i>Department of Dermatology, Fujita Health University School of Medicine</i>

Bibliographic Information

Other Title
  • 線維肉腫様変化を伴った巨大な隆起性皮膚線維肉腫の1例

Search this article

Abstract

A 42-year-old male noticed a subcutaneous small nodule in the abdomen 7 years ago. On the initial consultation in our department, a red, elastic-hard, cauliflower-like giant tumor measuring 17×16×9 cm was detected in the abdomen. The tumor surface was destroyed and hemorrhagic. Resection and mesh skin grafting were performed at an area horizontally 5 cm from the tumor peduncle margin. Since the border between the deep tumor area and rectus abdominis was partially unclear on magnetic resonance imaging, the anterior sheath of the rectus abdominis was also resected. In the totally extirpated specimen, CD34-negative, spindle tumor cells comprised approximately 70% of the tumor, showing a herringbone pattern, while CD34-positive, spindle tumor cells comprised the remaining 30%, showing a storiform pattern. COL1A1-PDGFB fusion gene was detected in the tumor tissue, and a diagnosis of dermatofibrosarcoma protuberans with fibrosarcomatous change was made. There has been no relapse or metastasis during the 1-year-and-2-month postoperative follow-up.[Skin Cancer (Japan) 2012 ; 27 : 339-344]

Journal

  • Skin Cancer

    Skin Cancer 27 (3), 339-344, 2013

    The Japanese Skin Cancer Society

References(4)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top