A case of dermatofibrosarcoma protuberans (DFSP)

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  • 隆起性皮膚線維肉腫の1例

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Description

A 39-year-old female had noticed the presence of a subcutaneous tumor in the right lower abdomen for three to four years. She visited our department on Jul. 17th, 2003, complaining of the rapid growth of the tumor without symptoms such as spontaneous pain or pruritus. Two solid dome-shaped tumors were closely situated to each other, with diameters of 8 and 5 cm respectively, and with slightly red and brownish smooth surfaces. No palpitation was noticed.<br>Histopathological examination biopsied from the two tumors revealed proliferation of numerous spindle cells with striform pattern with many mitoses, positive with anti-bimentin antibody and anti-CD34 antibody stain, and negative with anti-C-kit, S-100, or NSE antibodies, which was diagnosed as fibrosarcoma. Total resection of the uterus was carried out due to the discovery of multiple tumors inside of it under MRI examination. However, hysteromyoma was diagnosed histopathologically, so that wide total resection of the fibrosarcoma was performed, including the fascia tightly attached to the tumors, 5 cm away from the borderline of the tumors with mesh-graft skin transplantation on Sept. 30th, 2003. Three cycles of chemotherapy consisting of adriamycin and iphoomid were tried, and metastatic tumors or recurrent lesions have not been found after the resection. [Skin Cancer (Japan) 2005; 20: 318-322]

Journal

  • Skin Cancer

    Skin Cancer 20 (3), 318-322, 2005

    The Japanese Skin Cancer Society

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