A case of malignant melanoma on the back colliding with an intradermal nevus

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  • HIGASHIYAMA Reiichi
    Department of Dermatology, Chiba University Graduate School of Medicine
  • TOGAWA Yaei
    Department of Dermatology, Chiba University Graduate School of Medicine
  • SUEHIRO Keisuke
    Department of Dermatology, Chiba University Graduate School of Medicine
  • MARU Yugo
    Department of Dermatology, Chiba University Graduate School of Medicine
  • KAMADA Noriaki
    Department of Dermatology, Chiba University Graduate School of Medicine
  • KAMBE Naotomo
    Department of Dermatology, Chiba University Graduate School of Medicine
  • MATSUE Hiroyuki
    Department of Dermatology, Chiba University Graduate School of Medicine

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  • 真皮内母斑を伴った背部悪性黒色腫の1例

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<p>A 42-year-old woman noticed enlargement of a black macule on her back that had been present for over 20 years. We observed an asymmetric but well-defined macule, measuring 11× 7 mm, showing multiple shades of brown-black colors with a nodule on the upper side. Dermoscopic examination revealed irregular blotch with blue-whitish veil in the lower side of the lesion, atypical pigment network at the periphery of the entire lesion, and hypopigmented structureless area in the upper side nodule. Histopathologically, proliferation of atypical melanocytes positive for S-100 and HMB-45 stain was detected mainly in the epidermis and partly in the dermis of the lesion. However, in the nodule of the lesion, dermal nests of nevus cells negative for HMB-45 stain could be detected around appendix. We diagnosed malignant melanoma colliding with intradermal nevus although verifying whether the nevus was the origin of the melanoma was difficult.[Skin Cancer (Japan) 2016 ; 31 : 156-161]</p>

Journal

  • Skin Cancer

    Skin Cancer 31 (2), 156-161, 2016

    The Japanese Skin Cancer Society

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