History and new development of renin-angiotensin system-Why is the research important for physician?-

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  • Kagami Shoji
    Department of Pediatrics, Institute of Health Bioscience The University of Tokushima Graduate School of Medicine

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  • レニン・アンジオテンシン系（ＲＡＳ）の歴史と新展開―ｆｒｏｍ　ｂｅｎｃｈ　ｔｏ　ｂｅｄ：臨床医にとって，なぜ基礎研究が大切なのか―
  • —Why is the research important for physician ?—
  • —from bench to bed: 臨床医にとって, なぜ基礎研究が大切なのか—

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Abstract

 The classical renin-angiotensin system (RAS) is a circulating regulatory system for sodium balance, intravascular volume, and therefore blood pressure. There is increasing evidence that local RAS is situated in many organs, including kidney where it is involved in renal development, renal function and the progression of chronic kidney disease. This article briefly reviews the history and new development of RAS and indicates the importance of the research performed by physicians.

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