受精時におけるカルシウムイオン制御機構
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- 伊藤 潤哉
- 麻布大学獣医学部動物繁殖学研究室
書誌事項
- タイトル別名
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- Regulation of Calcium Signaling during Fertilization
- ジュセイジ ニ オケル カルシウムイオン セイギョ キコウ
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During fertilization, the sperm triggers resumption from the arrest, extrusion of the second polar body and pronuclear formation whose events are collectively acknowledged as ‘oocyte activation’. In mammalian species up to date, oocyte activation requires fertilization-associated increases in the intracellular concentration of calcium. These periodical rises are referred to as calcium oscillations. Result studies suggest that these calcium oscillations have important role in not only oocyte activation but also development of mammals. We focus on two molecules, phospholipase C zeta (PLCζ) and inositol 1,4,5-triphosphate receptor (IP3R) which have important role in regulation of calcium oscillations during fertilization in mammals. In this review, we will discuss present status and future perspective of molecular mechanism during fertilization in mammals.<br>
収録刊行物
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- 日本哺乳動物卵子学会誌
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日本哺乳動物卵子学会誌 29 (4), 146-154, 2012
日本卵子学会
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詳細情報 詳細情報について
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- CRID
- 1390282679317299200
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- NII論文ID
- 10031117485
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- NII書誌ID
- AN10548943
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- ISSN
- 13475878
- 13417738
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- NDL書誌ID
- 024039777
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- NDL
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