A case of rheumatoid arthritis treated with rituximab; rheumatoid factor was considered to be a useful relapse predictor

DOI
  • Imada Chiharu
    Department of Endocrinology, Metabolism, Rheumatology and Nephrology, Faculty of Medicine, Oita University
  • Ishii Koji
    Department of Endocrinology, Metabolism, Rheumatology and Nephrology, Faculty of Medicine, Oita University
  • Takano Kuniko
    Department of Medical Oncology and Hematology, Faculty of Medicine, Oita University
  • Omura Yuichi
    Department of Endocrinology, Metabolism, Rheumatology and Nephrology, Faculty of Medicine, Oita University
  • Ozaki Takashi
    Department of Endocrinology, Metabolism, Rheumatology and Nephrology, Faculty of Medicine, Oita University
  • Hamasaki Hajime
    Department of Endocrinology, Metabolism, Rheumatology and Nephrology, Faculty of Medicine, Oita University
  • Maeshima Keisuke
    Department of Endocrinology, Metabolism, Rheumatology and Nephrology, Faculty of Medicine, Oita University
  • Haranaka Miwa
    Department of Endocrinology, Metabolism, Rheumatology and Nephrology, Faculty of Medicine, Oita University
  • Ogata Masao
    Department of Medical Oncology and Hematology, Faculty of Medicine, Oita University
  • Shibata Hirotaka
    Department of Endocrinology, Metabolism, Rheumatology and Nephrology, Faculty of Medicine, Oita University

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Other Title
  • リツキシマブで治療し,リウマトイド因子が再燃予知因子として有用と考えられた関節リウマチの一例

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Abstract

<p>    A 68-year-old female was diagnosed with malignant lymphoma while undergoing treatment for rheumatoid arthritis (RA). She was started on chemotherapy including rituximab (RTX). Consequently, malignant lymphoma remitted, and RA improved. However, when RA recurred approximately 1 year after the chemotherapy, RTX treatment was repeated following which the symptoms disappeared, and this effect was maintained for about 1 year. RA recurred at an interval of approximately 1 year, and it improved each time with RTX treatment. Increase in rheumatoid factor was detected just before RA recurrences. Therefore, rheumatoid factor was considered to be a useful predictor of RA recurrence.</p>

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