A Case of Goblet Cell Carcinoid of the Appendix

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  • Watanabe Takafumi
    Third Department of Surgery, Tokyo Medical University Department of Surgery, Social Insurance Kamata General Hospital
  • Kasuya Kazuhiko
    Third Department of Surgery, Tokyo Medical University
  • Kuwabara Hiroshi
    Third Department of Surgery, Tokyo Medical University
  • Uchimura Norio
    Department of Surgery, Social Insurance Kamata General Hospital
  • Kato Fumiaki
    Third Department of Surgery, Tokyo Medical University Department of Surgery, Social Insurance Kamata General Hospital
  • Tsurui Shigeru
    Third Department of Surgery, Tokyo Medical University Department of Surgery, Social Insurance Kamata General Hospital
  • Katsumata Kenji
    Third Department of Surgery, Tokyo Medical University
  • Tsuchida Akihiko
    Third Department of Surgery, Tokyo Medical University

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  • 虫垂杯細胞カルチノイドの１例

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A 52-year-old man was admitted to our hospital complaining of right lower abdominal pain in late January 2013. On hematological examination the WBC count was 12,300/µl, CRP was 9.81mg/dl, and abdominal CT scan showed an enlarged appendix. On the next day, inspite of the administration of antibiotics WBC count and CRP were not decreased and symptoms became to worse. Therefore emergency appendectomy was performed, and a diagnosis of the goblet cell carcinoid of the appendix was obtained. He underwent a second laparotomy at the 28th day after the initial surgery. Operative finding showed peritoneal dissemination around adjacent peritoneum of the ileocecum and Douglas cavum. Ileocecal resection and D2 lymphadenectomy was performed. Pathological findings shows the goblet cell carcinoid of the appendix, SE, N3, H0, P2, M0, Stage Ⅳ. Eight months after surgery, the patient remains well without lung or hepatic metastasis and progression of peritoneal dissemination under the FOLFOX chemotherapy with bevacizumab. Goblet cell carcinoid of the appendix is a rare neoplasm showing histological features of both endocrine cells and mucinous adenocarcinoma cells. In advanced case, it shows poor prognosis due to induced lymph node metastasis or peritoneal dissemination.

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