A Resected Case of Pancreatic VIPoma Presenting with WDHA Syndrome

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  • WDHA症候群を呈した膵頭部VIP産生腫瘍の切除例

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A 65-year-old woman admitted to our hospital suffered severe diarrhea and weight loss. Our examinations revealed hypokalemia and high level of vasoactive intestinal polypeptide. Abdominal imaging demonstrated hypervascular mass measuring 40mm in pancreatic head, and a preoperative diagnosis of pancreatic VIPoma was made. Pylorus-preserving pancreato-duodenectomy was performed and the diagnosis was confirmed by immunohistochemical techniques. Serum VIP levels declined and hypokalemia and diarrhea improved after operation. She has not experienced a reccurence until 3 years and 9 months.

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