A Case of Multiple Osteonecrosis During Treatment for ITP.

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  • 特発性血小板減少性紫斑病（ＩＴＰ）治療経過中に多発性骨壊死を来した１症例

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We present a case of multiple osteonecrosis experienced during treatment for idiopathic thrombocytopenic purpula. The patient was a 51 year-old woman. A diagnosis of ITP was made in Dec. 1981, and she had received a large dose of steroids (9280mg) for five years. From 1982 to 1991, osteonecrosis appeared in the right femoral head and another nine sites. Roentgenogram, bone scan, and MRI demonstrated necrotic lesions. Pathological examination revealed that a biopsy specimen was necrotic tissue. Many cases of steroid induced osteonecrosis have been reported, but such a case induced by steroid treatment for ITP is rare.

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