遠赤外線全身温熱加温器による末期癌の治療成績

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  • Evaluation of therapy efficacy according to the Far-Infrared Whole-Body Hyperthermia Heat Divice.

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From February 1991 to May 1995, we performed whole-Body hyperthermia (WBH) therapy 954 times in a total of 167 patients with advanced carcinoma using the U. S. by Enthermics Medical Systems Inc. At this time, we report our assessment of the efficacy of treatment in 112 patients who completed more than one course of WBH therapy. The therapy was performed in 52 male and 60 female patients aged 2080 years. Primary Carcinoma were the lung, colon, breast, stomach, kidney, uterus, liver, ovary, pancreas and others. The therapy was generally once a week performed in outpatients, who were given one course (4 times). The patients received intravenous anesthesia to achieve a somnolent state during the warming-up stage. Body temperature was measured in the esophagal, intrarectaly and at four sites of the body surface. The patients received WBH therapy for one hour (three to four hours for a complete course) with intraesophagal temperature maintained at 41.8°C. To judge the efficacy of the therapy, evaluation was made based on systemic criteria assessed by methods including the Karnofsky Index in addition to the UICC that was generally in use. A survey was conducted also to assess the rating of improvement in Quality of Life (QOL) through questionnaires. The efficacy rate according to the UICC was 75% for “significantly effecticve” together and “effective” and the using the systemic criteria was 81.3% in total. Improvement in QOL was evaluated in three stages : “excellent”, “good” and “no change”. QOL was rated as “excellent” or “good” by 78.5% of the patients. The efficacy rating used systemic criteria was higher than that used the UICC ; This was considered to result from an improvement in the Karnofsky Index due to recovery from pain. It was suggested that both the QOL evaluation and the systemic criteria were effective for judging the efficacy of this therapy, which led to a significant recovery of activity due to improvement in general condition.

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