A Case of Laryngeal Amyloidosis Suspected as an Epithelial Tumor

DOI 2 Citations 36 References Open Access
  • Yokoi Hidenori
    Department of Otorhinolaryngology, Juntendo University Urayasu Hospital
  • Tayama Niro
    Department of Otorhinolaryngology, Tracheo-esophagology, International Medical Center of Japan
  • Sakai Yoko
    Department of Otorhinolaryngology-Head and Neck Surgery, Juntendo University School of Medicine
  • Sugita Gen
    Department of Otorhinolaryngology-Head and Neck Surgery, Juntendo University School of Medicine
  • Hayashi Chieri
    Department of Otorhinolaryngology-Head and Neck Surgery, Juntendo University School of Medicine
  • Minekawa Akira
    Department of Otorhinolaryngology-Head and Neck Surgery, Juntendo University School of Medicine
  • Ikeda Katsuhisa
    Department of Otorhinolaryngology-Head and Neck Surgery, Juntendo University School of Medicine

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  • 上皮性腫瘍を疑った喉頭アミロイドーシスの 1 例

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We reported on the case of a 50-year-old male with localized amyloidosis of the larynx. He was referred to us because he had a two and a half year history of odynophagia and hoarseness. A dark brown elevated lesion was detected on his false vocal cord and laryngeal ventricle. We performed laryngomicrosurgery under general anesthesia and resected the mass to the maximum extent. Histopathological findings with hematoxylin and congo red stain revealed amyloidosis. Immunohistopathological analysis showed chemical classification as AL type, lamda chain. Extensive examinations excluded systemic amyloidosis. The patient showed a favorable outcome and there was no recurrence two and half years after surgery.<BR>　We also reviewed the diagnostic approach, treatment and follow up of amyloidosis.

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