Biosensing technology for cellular and tissular responses
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- IKENO Shinya
- Department of Biological Functions and Engineering, Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology CREST, Japan Science and Technology Agency
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- HARUYAMA Tetsuya
- Department of Biological Functions and Engineering, Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology CREST, Japan Science and Technology Agency
Bibliographic Information
- Other Title
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- 細胞・組織バイオセンシング技術の進展
- サイボウ ソシキ バイオセンシング ギジュツ ノ シンテン
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Abstract
Cells correspond to the minimum functional unit in the organism living system and respond first to the chemical and physical stimulus. Such signals might be useful as parameters for recognition of living system status which is damaged by various factors, and the detection will be applicative for chemical information for its safety, drug efficacy profile. However, such cellular signals are very week and intractable detected using conventional analytical methods. Recently, developments of technology such as nanotechnology, molecular designing, genetic engineering, cellular and tissue engineering etc., have been brought the great contribution for life science such as research of medicine, molecular biology. Bioimaging using fluorescence probes are enable to easily visible detection for cellular and tissular function, and more functional cells translated by gene cloning technology have brought to sharply extend the possibility of cellular biosensing. Using new technology of biosensor, cellular and tissular function have been detected in situ. This review paper includes cellular biosensing technologies response to either toxic compounds or chemicals being considered for a medicinal drug for humans.<br>
Journal
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- BUNSEKI KAGAKU
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BUNSEKI KAGAKU 53 (3), 135-146, 2004
The Japan Society for Analytical Chemistry
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Keywords
Details 詳細情報について
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- CRID
- 1390282679330911232
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- NII Article ID
- 110002905348
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- NII Book ID
- AN00222633
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- COI
- 1:CAS:528:DC%2BD2cXisFynurg%3D
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- NDL BIB ID
- 6889189
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- ISSN
- 05251931
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- NDL-Digital
- CiNii Articles
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- Abstract License Flag
- Disallowed