A case of metaplastic thymoma

DOI 20 References
  • Arimura Takaaki
    Department of Respiratory Surgery, Nagano Municipal Hospital
  • Sakaizawa Takao
    Department of Respiratory Surgery, Nagano Municipal Hospital
  • Nishimura Hideki
    Department of Respiratory Surgery, Nagano Municipal Hospital
  • Hamanaka Kazutoshi
    Department of Surgery, Division of Thoracic Surgery, Shinshu University School of Medicine
  • Yoshida Kazuo
    Department of Surgery, Division of Thoracic Surgery, Shinshu University School of Medicine
  • Amano Jun
    Department of Surgery, Division of Thoracic Surgery, Shinshu University School of Medicine

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  • Metaplastic thymomaの1例

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A 40-year-old woman had an abnormal shadow on a chest radiograph.<br>A computed tomography scan showed a well-circumscribed anterior mediastinal tumor with heterogeneous enhancement with a longitudinal diameter of 59 mm, and fluorodeoxyglucose-positron emission tomography (FDG-PET) showed abnormal accumulation. The tumor was diagnosed as type A or type B thymoma by needle biopsy.<br>The patient underwent resection via a median sternotomy. Pathological examination revealed a characteristic biphasic architecture consisting of islands of epithelioid cells and surrounding bundles of spindle cells. Immunohistochemical staining showed that while the epithelial cells were strongly positive for cytokeratin, the spindle cells were weakly positive. The final diagnosis of the patient's condition was metaplastic thymoma.<br>We report a rare case of metaplastic thymoma.

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