A case of neuroblastoma of the anterior mediastinum in an 81-year-old woman
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- Takahashi Tsuyoshi
- 京都大学大学院 医学研究科呼吸器外科学
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- Sakamoto Jin
- Department of General Thoracic Surgery, Shimane Prefectural Central Hospital
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- Miyamoto Nobuhiro
- 京都大学大学院 医学研究科呼吸器外科学
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- Kosaka Shinji
- Department of General Thoracic Surgery, Shimane Prefectural Central Hospital
Bibliographic Information
- Other Title
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- 高齢者における前縦隔神経芽腫の一例
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Description
An 81-year-old woman was pointed out as having an abnormal shadow on chest X-ray. Computed tomography revealed a highly calcified mass lesion in the right anterior mediastinum that was 40 mm in size, and another in the left 30 mm in size. She underwent mass resection with extended thymectomy. Neither mass showed severe adhesion to adjacent organs and both could be completely resected except for the left phrenic nerve. Pathological findings of the left mass showed small round tumor cells, and further immunohistological staining revealed that the tumor cells were positive for neuron-specific enolase, S-100 protein and synaptophysin but negative for cytokeratin, MIC-2, UCHL-1 and L-26, therefore we diagnosed this tumor as a neuroblastoma. Pathological findings of the right mass showed only necrosis and calcification, with no viable cells. Following the operation, 46 Gy of irradiation was performed. About four years after the resection, she died due to the recurrence in the left hemithorax and multiple bone metastases. Neuroblastoma found in an octogenarian is extremely rare, and that arising in the anterior mediastinum is also uncommon.
Journal
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- The Journal of the Japanese Association for Chest Surgery
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The Journal of the Japanese Association for Chest Surgery 22 (4), 696-700, 2008
The Japanese Association for Chest Surgery
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Details 詳細情報について
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- CRID
- 1390282679336939776
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- NII Article ID
- 110006783304
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- NII Book ID
- AN10467885
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- ISSN
- 18814158
- 09190945
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed