Intracavitary instillation of urokinase for empyema and parapneumonic pleural effusion
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- Nakagawa Taku
- Department of General Thoracic Surgery, Senboku Kumiai General Hospital
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- Konno Hayato
- Department of General Thoracic Surgery, Senboku Kumiai General Hospital
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- Sasaki Tomohiko
- Department of General Thoracic Surgery, Senboku Kumiai General Hospital
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- Oyama Norio
- Department of General Thoracic Surgery, Senboku Kumiai General Hospital
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- Ito Manabu
- Department of General Thoracic Surgery, Akita University School of Medicine
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- Saito Hajime
- Department of General Thoracic Surgery, Akita University School of Medicine
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- Minamiya Yoshihiro
- Department of General Thoracic Surgery, Akita University School of Medicine
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- Ogawa Junichi
- Department of General Thoracic Surgery, Akita University School of Medicine
Bibliographic Information
- Other Title
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- 膿胸および肺炎随伴性胸水に対するウロキナーゼ胸腔内注入療法の検討
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Description
Some reports have shown that thoracoscopic surgery for fibrinopurulent empyema with multiloculation and fibrinous and viscous fluid often leads to complete drainage. However, some patients cannot undergo surgical treatment because of their poor condition. Some papers have indicated that the intracavitary instillation of urokinase is a useful method for these cases. However, this has not been investigated sufficiently to become a standard method. In this paper, we report five patients who underwent the intracavitary instillation of urokinase for fibrinopurulent empyema. All patients showed empyema with multiloculated empyemic fluid and pleural thickening. Four of the five patients could achieve the relief of fluid accumulation after urokinase instillation (120,000 IU X 6-9 times). The other patient recovered after the instillation of urokinase followed by surgical treatment. The intracavitary instillation of urokinase was performed 1-16 days after the onset of empyema in the former 4 patients, and one month after in the latter one. All patients recovered without major complications. This procedure might be useful for the treatment of fibrinopurulent empyema in high-risk patients.
Journal
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- The Journal of the Japanese Association for Chest Surgery
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The Journal of the Japanese Association for Chest Surgery 24 (4), 733-741, 2010
The Japanese Association for Chest Surgery
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Details 詳細情報について
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- CRID
- 1390282679338874368
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- NII Article ID
- 10026475724
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- NII Book ID
- AN10467885
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- ISSN
- 18814158
- 09190945
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed
