歩行運動中の経頭蓋的磁気刺激を高精度で実現するための刺激コイル定位システムの開発

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  • Development of the TMS Coil Navigation System for Precise Measurement of Motor Evoked Potentials during Walking

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Transcranial magnetic stimulation (TMS) is one of the useful tools as an electrophysiological technique to elucidate neural mechanism underlying human behavior. In order to acquire validated motor evoked potentials (MEPs) during dynamic motion such as walking, it is necessary to precisely place TMS coil to the target on subjects' scalp. In this study, we developed a coil navigation system for accomplishing precise coil placement even though the subject's head is moved. Since the system enables us to record the coil position data, it is possible to ascertain whether the coil is suitably placed on the target or not. In order to evaluate the feasibility of the use of our system, sham TMS was applied during treadmill walking with or without using the developed system. The results demonstrated that the variances of coil location and distance from the target site (consistent error) could be minimized with using the system. Our developed coil navigation system enabled us to realize high precision and accuracy in TMS coil placement even during walking.

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