A Measurement Method of Uptakes for Volatile Chlorinated Hydrocarbons to Respiratory Organs.

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  • ガス状有機塩素系化合物の呼吸器内吸収率の測定法

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The uptakes of five volatile chlorinated hydrocarbons (VCHs) into respiratory organs were evaluated at similar concentrations to those in environmental air. Trichloroethylene (TRI), 1, 1, 1-trichloroethane (111TRI), tetrachloroethylene (PERC), tetrachloromethane (TCM), and chloroform (CHLO), in n-hexane solution were vaporized in an office (68m3) . Then, the room air as inhaled air and exhaled air from a volunteer were simultaneously collected with 2L and 1L of Tedlar Bags, respectively, at several time-intervals. All samples were directly analyzed by GC/ECD. The concentration of each of VCHs in both inhaled air and exhaled air was measured as a function of the sampling time, and the time -average uptake of each of VCHs into respiratory organs was evaluated: TRI, 50.6±5.8%; CHLO, 47.7±5.9%; PERC, 38.6±10.8%; TCM, 24.8±10.4%; 111TRI, 19.8±7.7%.

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