マウスゲノムとの比較遺伝子地図を用いた末マッピング遺伝子の染色体の予測

  • 和田 康彦
    農林水産省畜産試験場育種部家畜ゲノム研究チーム
  • 岸野 洋久
    東京大学大学院農学生命科学研究科生物測定学研究室
  • 柏木 宣久
    統計数理研究所調査実験解析研究系

書誌事項

タイトル別名
  • Using Linkage Map of Mouse for Prediction of Gene Location in Animals

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説明

The high-density linkage map of mouse has been constructed. This map contains quantitative trait loci (QTL) and major genes which are not mapped on other animals. In this study, a Bayesian model was developed to predict the chromosome number of unmapped genes in animals using comparative mapping data in contrast with mouse linkage map. The comparative mapping data of mouse-human, mouse-rat and mouse-cattle is collected from the Animal Genome Database. In order to examinethe accuracy of our method, we randomly divided the data into two subsets. The ratios of chromosomal translocation of mouse-human, mouse-rat and mouse-cattle were estimated by one of the subsets, and the chromosome numbers of mapped genes of human, rat and cattle were predicted for another subset.

収録刊行物

  • 計量生物学

    計量生物学 20 (2), 193-200, 2000

    日本計量生物学会

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詳細情報 詳細情報について

  • CRID
    1390282679346451072
  • NII論文ID
    130002151922
  • DOI
    10.5691/jjb.20.193
  • ISSN
    21856494
    09184430
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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