Coagulation-fibrinolysis Activity is not Accelerated in Patients with Diffuse Axonal Injury
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- Takaoka Makoto
- Osaka prefectural Nakakawachi Medical Center of Acute Medicine
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- Tabuse Hisayuki
- Osaka prefectural Nakakawachi Medical Center of Acute Medicine
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- Tohma Yoshiki
- Osaka prefectural Nakakawachi Medical Center of Acute Medicine
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- Nakajima Shin
- Osaka prefectural Nakakawachi Medical Center of Acute Medicine
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- Kishimoto Masafumi
- Osaka prefectural Nakakawachi Medical Center of Acute Medicine
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- Onaka Atsuhiko
- Osaka prefectural Nakakawachi Medical Center of Acute Medicine
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- Yajima Yuichi
- Osaka prefectural Nakakawachi Medical Center of Acute Medicine
Bibliographic Information
- Other Title
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- びまん性軸索損傷では,脳挫傷にみられる顕著な凝固線溶亢進状態が認められない
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Abstract
Background: The plasma level of D-dimer (DD) on admission is useful as a prognostic marker of head injury. Methods: Eighty patients with isolated blunt head trauma were grouped according to the type of brain parenchymal injury using MRI. The differences in the DD levels among the groups, and the correlation between the DD levels and the patients' outcome, were investigated. Results: All patients were categorized into the following groups: diffuse axonal injury (DAI, n=24), cerebral contusion (CON, n=47), and no intraparenchymal lesion (NIL, n=9). The DD level was significantly higher in the CON-group than in the other two groups. In the CON-group, the patients with an unfavorable outcome had significantly higher DD levels. In the DAI-group, however, the DD level remained generally low regardless of the outcome. Conclusions: The DD level was sensitive to the type of brain injury. In the DAI-group, however, the coagulation-fibrinolysis activity was not accelerated to as great an extent as it was in the CON-group, therefore even the DD level was not a good prognostic indicator.
Journal
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- Nihon Kyukyu Igakukai Zasshi
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Nihon Kyukyu Igakukai Zasshi 15 (7), 243-249, 2004
Japanese Association for Acute Medicine
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Details 詳細情報について
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- CRID
- 1390282679346906496
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- NII Article ID
- 130003437648
- 10013777134
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- NII Book ID
- AN10284604
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- ISSN
- 18833772
- 0915924X
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- Text Lang
- en
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed