書誌事項
- タイトル別名
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- Effects of Vitamin D Metabolites on Mineralization of Embryomic Chick Femurs In Vitro.
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説明
We examined the effects of vitamin D metabolites on mineralization of the 10-day embryonic chick femurs in organ culture system. When 5-day cultures kept in the control medium were cultured in the several mediums containing 1α (OH) D3, 1, 25 (OH) 2D3 or 24, 25 (OH) 2D3 at concentration of 10-11-10-8 M during an additional 5 days, the mineralization of cultured bones increased in the treatment with 1α (OH) D3 at concentration of 10-10-10-8M, and decreased in the treatment with 1, 25 (OH) 2D3 at concentration of 10-10-10-8 M, and was no change in the treatment with 24, 25 (OH) 2D3. The activities of both alkaline phosphatase and acid phosphatase did not change in the cultured bones with vitamin D metabolites. These results suggested that 1α (OH) D3 increased bone formation, 1, 25 (OH) 2D3 stimulated bone resorption, and 24, 25 (OH) 2D3 had no effect to bone-remodeling in this organ culture system.
収録刊行物
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- 日本疾患モデル学会記録
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日本疾患モデル学会記録 13 53-57, 1997
公益社団法人 日本実験動物学会
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詳細情報 詳細情報について
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- CRID
- 1390282679349533184
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- NII論文ID
- 130000760739
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- ISSN
- 18844197
- 09188991
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
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- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可
