Pressure-induced Interdigitation in Phospholipid Bilayer Membranes

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  • リン脂質二分子膜における圧力誘起指組み構造形成
  • リン シシツ 2ブンシマク ニ オケル アツリョク ユウキ ユビグミ コウゾウ ケイセイ

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Abstract

Pressure studies on the bilayer phase transitions of ester-linked diacylphosphatidylcholines (diacyl-PCs) and ether-linked dialkyl-PCs are reviewed. Comparing the bilayer phase diagrams and the thermodynamic quantities of phase transitions for diacyl-PCs with those for dialkyl-PCs, the difference in lateral interaction between polar head groups of diacyl-PC and dialkyl-PC was elucidated. The mechanism of bilayer interdigitation induced by high-pressure, which is characteristic of phospholipids with a choline head group, is discussed on the basis of molecular interaction in lipid bilayer membranes.

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