Hydrolysis of Prostaglandin E<sub>1</sub> Methyl Ester and Its Analogues with Pig Liver Esterase

DOI Web Site Web Site 1 Citations

Bibliographic Information

Other Title
  • エステラーゼを用いるE型プロスタグランジンメチルエステルの加水分解
  • エステラーゼを用いるE型プロスタグランジンメチルエステルの加水分解(ノート)
  • エステラーゼ オ モチイル Eガタ プロスタグランジンメチルエステル ノ カス
  • プロスタグランジンの化学　ＸＩＸ　　エステラーゼを用いるＥ型プロスタグランジンメチルエステルの加水分解

Search this article

Description

Prostaglandin [1] methel ester (1) and its analogues [2] and [ 3] were easiliy hydrolyzed with pig liver esterase. In this hydrolysis, saturated esters [1] and [ 2] were hydrolyzed about 15 times faster than a, 8-unsaturated ester [ 3]. In the hydrolysis of three other esters [4], [5] and[ 6], the reaction rate decreased in order: saturated ester [4]trans-α, β-unsaturated ester [5], and cis-α, β-unsaturated ester[6]. In comparison with other enzymatic hydrolysis, this method has the advantages of no side reaction and availability of higher substrate concentration.

Journal

  • NIPPON KAGAKU KAISHI

    NIPPON KAGAKU KAISHI 1983 (9), 1390-1392, 1983-09-10

    The Chemical Society of Japan

Citations (1)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top