The Experimental Study for The Effect of Sodium Copper Chlorophyllin in Halitosis

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  • 銅クロロフィリンナトリウムの口臭抑制効果
  • 唾液による実験的研究

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The purpose of this study was to clarify the effect of sodium copper chlorophyllin (Chn.) for halitosis.<br>Volatile sulphur compounds (V. S. C) produced during the incubation of whole saliva were analyzed by gas chromatograph. The changing of leucocytes and epithelial cells in incubated whols saliva were observed using microscope. The effect of anti-bacteria against oral anaerobic bacteria was also observed.<br>The following conclusions were obtained as the result of judging the halitosis control effect of Chn. by its experimental use of the saliva of periodontal patients having halitosis<br>1. By adding and incubating 100mg, 50mg, 10mg and 5mg Chn. respectively into 1ml saliva, V. S. C. were not detected. However, when sampled at 1mg addition under the condition of incubate 36 and 48 hours, a small amount of V. S. C. was detected.<br>2. The destruction speed of cellular components by incubate, in comparision with a controlled group, was not effected by addition of Chn.<br>3. By microscopic observation, cell attachment on obsorption of Chn. were found which suggested its combination with protein.<br>4. Almost any effect of anti-bacteria or bacteria growth prevention against oral anaerobic bacteria of Chn. was not observed.

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