Periodoal Disease and Resistance Factor, I, Immunopathological Study for Detection of Antibiotic Factors in the Pocket Fluid
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- TAKEUCHI Hiroshi
- Department of Oral Pathology, Gifu college of Dentistry
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- KANEHISA Junya
- Department of Oral Pathology, Gifu college of Dentistry
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- HORI Yasunori
- Department of Oral Pathology, Gifu college of Dentistry
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- UEDA Masatoshi
- Department of Periodontology, Osaka Dental University
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- IMAI Hisao
- Department of Periodontology, Osaka Dental University
Bibliographic Information
- Other Title
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- 歯周疾患と抵抗因子・第1編, 歯周ポッケトにおける抗菌因子の免疫病理学的観察
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Abstract
This study was made to clarify the existense of antibiotic factors to oral bacteria in the gingival pocket fluid of individuals with periodontal disease by using fluorescent antibody techniques. Fluorescein-labeled antisera were obtained from human oral bacteria, Clq, C3, properdin, IgG, IgA, IgM, IgD, IgE, Fab, fibrinogen, and serious frozen sections were stained by them.<br>The results were as follows:<br>1) Each substance was detcted in the bacterial mass as showing Table 1 and Fig. 1.<br>2) IgG, IgA, Fab, and fibrinogen were demonstrated most frequently as Fig. 3.<br>From above results, we arrived at following conclusions:<br>1) Main defensive system to the oral bacteria in the gingival pocket were immunoglobulins and activated complement system.<br>2) The complement was the alternative pathway in addition to classical pathway.<br>3) We were suggested that both complement systems raised to activity of phagocytosis, and finally caused to bacterial lysis in the gingival pocket.
Journal
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- Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)
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Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) 23 (4), 610-615, 1981
JAPANESE SOCIETY OF PERIODONTOLOGY
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Details 詳細情報について
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- CRID
- 1390282679390202496
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- NII Article ID
- 110006204328
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- NII Book ID
- AN0019129X
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- ISSN
- 1880408X
- 03850110
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- PubMed
- 7042860
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed