A Mixed Apocrine Gland Tumor with Metastases to the Bone and Bone Marrow in a Miniature Poodle
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- Morita Reiko
- Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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- Jin Meilan
- Division Pathology, Biological Safety Research Center, National Institute of Health Sciences
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- Ogawa Bun-ichiro
- Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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- Kuwata Kazunori
- Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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- Shibutani Makoto
- Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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- Mitsumori Kunitoshi
- Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology
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説明
A 10-year-old female miniature poodle had a mass in its carpal joint of the left forelimb. The tumor was divided into small multiple lobules by delicate connective tissues, and necroses were found in some of the central lobules. In some connective stromal areas, chondroid and osteoid tissues were formed. The tumor cells were similar to the structure of apocrine gland epithelial cells with apical blebs resembling apocrine secretion and eosinophilic secretary materials within the luminal space, and spindle cells were sometimes found in the basal area of the glandular structure. In some areas, tumor cells invaded in the blood vessels, bone and bone marrow. Immunohistochemically, the tumor cells forming tubulo-acinar to solid structures were intensely positive for cytokeratin and keratin K8/K18, and the spindle cells were positive for vimentin and alpha-smooth muscle actin. This case was diagnosed as a malignant mixed apocrine gland tumor with metastases to the bone and bone marrow. <br>
収録刊行物
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- Journal of Toxicologic Pathology
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Journal of Toxicologic Pathology 23 (2), 95-98, 2010
日本毒性病理学会
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詳細情報 詳細情報について
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- CRID
- 1390282679392296064
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- NII論文ID
- 10030978796
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- NII書誌ID
- AN10232280
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- ISSN
- 1881915X
- 09149198
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- NDL書誌ID
- 10756748
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可