Spontaneous Extraskeletal Osteosarcoma in a Rabbit (Oryctolagus cuniculus) : Histopathological and Immunohistochemical Findings
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- WIJESUNDERA Kavindra Kumara
- Laboratory of Veterinary Pathology, Division of Veterinary Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, 1-58 Rinku-oraikita, Izumisano City, Osaka 598-8532, Japan
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- IZAWA Takeshi
- Laboratory of Veterinary Pathology, Division of Veterinary Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, 1-58 Rinku-oraikita, Izumisano City, Osaka 598-8532, Japan
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- FUJITA Daisuke
- Kitasuma Animal Hospital, 9-5-8 Yokoo, Suma-ku, Kobe City, Hyogo 654-0131, Japan
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- DENDA Yuki
- Kitasuma Animal Hospital, 9-5-8 Yokoo, Suma-ku, Kobe City, Hyogo 654-0131, Japan
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- SETO Eiko
- Kitasuma Animal Hospital, 9-5-8 Yokoo, Suma-ku, Kobe City, Hyogo 654-0131, Japan
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- HIROSHI Sasai
- Kitasuma Animal Hospital, 9-5-8 Yokoo, Suma-ku, Kobe City, Hyogo 654-0131, Japan
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- KUWAMURA Mitsuru
- Laboratory of Veterinary Pathology, Division of Veterinary Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, 1-58 Rinku-oraikita, Izumisano City, Osaka 598-8532, Japan
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- YAMATE Jyoji
- Laboratory of Veterinary Pathology, Division of Veterinary Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, 1-58 Rinku-oraikita, Izumisano City, Osaka 598-8532, Japan
書誌事項
- タイトル別名
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- Spontaneous Extraskeletal Osteosarcoma in a Rabbit (<i>Oryctolagus cuniculus</i>): Histopathological and Immunohistochemical Findings
この論文をさがす
抄録
A spontaneously occurring subcutaneous mass in the left forelimb of a nine-year-old rabbit (Oryctolagus cuniculus) was examined histopathologically and immunohistochemically. Clinically, edema and hemorrhage were seen around the mass. No connection of the tumor mass to the appendicular skeleton was found. The tumor was arranged in a solid growth pattern and irregular bundles, and neoplastic cells were polygonal to spindle-shape. Osteoid (positive for osteocalcin) and multinucleated giant cells were diffusely or focally seen. Neoplastic cells were positive for vimentin, osterix and Ki-67, indicating the nature of osteoblasts with proliferating activity, but negative for α-smooth muscle actin, desmin or CD204. Based on these findings, a diagnosis of extraskeletal osteosarcoma was made, a very rare tumor both in laboratory and pet rabbits.
収録刊行物
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- Journal of Toxicologic Pathology
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Journal of Toxicologic Pathology 26 (3), 309-312, 2013
日本毒性病理学会
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詳細情報 詳細情報について
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- CRID
- 1390282679392644736
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- NII論文ID
- 130003382450
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- NII書誌ID
- AN10232280
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- COI
- 1:STN:280:DC%2BC2c%2FpsV2ltg%3D%3D
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- ISSN
- 1881915X
- 09149198
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- NDL書誌ID
- 024937280
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- PubMed
- 24155564
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可