Effects of NMDA application for the neural activity of mesencephalic trigeminal neurons

DOI 19 References
  • ENOMOTO Akifumi
    First Department of Oral Maxillofacial Surgery, Osaka University Graduate School of Dentistry Department of Oral Maxillofacial Surgery, Kinki University School of Medicine
  • OKAMOTO Reiko
    First Department of Oral Maxillofacial Surgery, Osaka University Graduate School of Dentistry
  • SENOO Hitomi
    First Department of Oral Maxillofacial Surgery, Osaka University Graduate School of Dentistry
  • KUSAYAMA Morio
    First Department of Oral Maxillofacial Surgery, Osaka University Graduate School of Dentistry
  • HAMADA Suguru
    First Department of Oral Maxillofacial Surgery, Osaka University Graduate School of Dentistry Department of Oral Maxillofacial Surgery, Kinki University School of Medicine
  • KOGO Mikihiko
    First Department of Oral Maxillofacial Surgery, Osaka University Graduate School of Dentistry

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  • NMDA誘発性顎運動時の三叉神経中脳路核ニューロンの神経活動

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Abstract

The electrophysiological properties of mesencephalic trigeminal (Mes V) neurons in NMDA-induced trigeminal activity are still unknown. In this study we show how NMDA application affects Mes V neural activity. Additionally, we investigated the properties of subthreshold sodium currents (persistent and resurgent sodium currents) under NMDA application. NMDA application blocked rhythmical burst discharge and reduced the flow of subthreshold sodium currents in Mes V neurons.<br>

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