脳ドックでの超音波血流測定による頭蓋内外動脈硬化の診断―とくにＰＩ値の意義について―

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タイトル別名
  • Diagnosis of Extra- and Intracranial Vessel Arteriosclerosis by Transcranial Doppler Ultrasonography at Routine Brain Check-up
  • ―とくにPI値の意義について―

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We studied 1, 282 persons (age range: 29 to 83 years; mean age ± S.D: 45.8± 14.7 years; male: female ratio: 678: 604) who underwent routine health check-ups at our hospital for detection of asymptomatic brain diseases. According to the presence or absence of arteriosclerosis (AS) on MRA, the subjects were divided into an AS group (564 subiects) and a non-AS group (718 subjects), and then (1) mean age, (2) systemic blood pressure, including systolic blood, pressure (SBP), diastolic blood pressure (DBP), and pulse pressure (PP), and (3) mean blood flow velocity (mFV) and PI value (PI) obtained at the common carotid artery (CA) and middle cerebral artery (MCA) using transcranial Doppler ultrasonography (TC2-64; Rikoh Shoji) were compared between the two groups.<BR>(1) The mean age in the AS group (66.8±8.9 years) was significantly higher than in the non-AS group (47.9±13.4 years) (p<0.02) . (2) The mean values of SBP, DBP, and PP were found to be 156.5 ± 9.8 mmHg, 77.5 ± 10.2mmHg, and 67.5 ± 7.4mmHg, respectively, in the AS group, and 132.25 ± 12.6mmHg, 72.5 ± 7.8mmHg, and 47.5 ± 8.0mmHg, respectively, in the non-AS group, revealing significantly higher SPB and PP values in the AS group (p<0.05 and p<0.02, respectively) . (3) mFV at the CA and MCA did not differ significantly between the AS and non-AS groups. PI at the CA and MCA was determined be 1.01 ± 0.28 and 0.81 ± 0.32, respectively, in the AS group, and 0.67 ± 0.19 and 0.58 ± 0.24, respectively, in the non-AS group, revealing significantly higher PI in the AS group (p<0.02, p<0.05) . It was noteworthy that all subjects having a PI of 1.0 or higher were included in the AS group.

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