Cloning, characterization and expression of cDNA containing major histocompatibility complex class I, II.ALPHA. and II.BETA. genes of Japanese flounder Paralichthys olivaceus
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- SRISAPOOME PRAPANSAK
- Laboratory of Genome Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology
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- OHIRA TSUYOSHI
- Laboratory of Genome Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology
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- HIRONO IKUO
- Laboratory of Genome Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology
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- AOKI TAKASHI
- Laboratory of Genome Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology
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説明
The nucleotide sequences of Japanese flounder Paralichthys olivaceus, major histocompatibility complex (MHC) cDNA, classical MHC class Iα, non-classical MHC class Iβ, MHC class IIα and IIβ, were determined. The domain structures and antigen binding motifs of vertebrate MHC are conserved in the Japanese flounder MHC. A phylogenetic analysis supports the classification of these genes into class I and class II MHC. Classical MHC class Iα was ubiquitously expressed, whereas the non-classical MHC class Iβ was expressed mainly in lymphoid organs, gills, intestine and stomach. The MHC classes IIα and IIβ were also ubiquitously expressed.
収録刊行物
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- Fisheries science
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Fisheries science 70 (2), 264-276, 2004
公益社団法人 日本水産学会
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詳細情報 詳細情報について
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- CRID
- 1390282679405143552
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- NII論文ID
- 130003904061
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- COI
- 1:CAS:528:DC%2BD2cXjvFyqsbg%3D
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- ISSN
- 14442906
- 09199268
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
- OpenAIRE
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- 抄録ライセンスフラグ
- 使用不可