Cloning, characterization and expression of cDNA containing major histocompatibility complex class I, II.ALPHA. and II.BETA. genes of Japanese flounder Paralichthys olivaceus

DOI 2 Citations 49 References
  • SRISAPOOME PRAPANSAK
    Laboratory of Genome Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology
  • OHIRA TSUYOSHI
    Laboratory of Genome Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology
  • HIRONO IKUO
    Laboratory of Genome Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology
  • AOKI TAKASHI
    Laboratory of Genome Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology

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Description

The nucleotide sequences of Japanese flounder Paralichthys olivaceus, major histocompatibility complex (MHC) cDNA, classical MHC class Iα, non-classical MHC class Iβ, MHC class IIα and IIβ, were determined. The domain structures and antigen binding motifs of vertebrate MHC are conserved in the Japanese flounder MHC. A phylogenetic analysis supports the classification of these genes into class I and class II MHC. Classical MHC class Iα was ubiquitously expressed, whereas the non-classical MHC class Iβ was expressed mainly in lymphoid organs, gills, intestine and stomach. The MHC classes IIα and IIβ were also ubiquitously expressed.

Journal

  • Fisheries science

    Fisheries science 70 (2), 264-276, 2004

    The Japanese Society of Fisheries Science

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Keywords

Details 詳細情報について

  • CRID
    1390282679405143552
  • NII Article ID
    130003904061
  • DOI
    10.1111/j.1444-2906.2003.00800.x
  • COI
    1:CAS:528:DC%2BD2cXjvFyqsbg%3D
  • ISSN
    14442906
    09199268
  • Text Lang
    en
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
    • OpenAIRE
  • Abstract License Flag
    Disallowed

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