"Myo Lab": A JAXA Cell Biology Experiment in "Kibo (JEM)" of the International Space Station
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- Harada-Sukeno Akiko
- Department of Nutritional Physiology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan
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- Kohno Shohei
- Department of Nutritional Physiology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan
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- Nakao Reiko
- Department of Nutritional Physiology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan
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- Hirasaka Katsuya
- Department of Nutritional Physiology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan
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- Higashibata Akira
- Japan Aerospace Exploration Agency (JAXA), 2-1-1 Sengen, Tsukuba, Ibaraki 305-8505, Japan
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- Yamazaki Takashi
- Japan Aerospace Exploration Agency (JAXA), 2-1-1 Sengen, Tsukuba, Ibaraki 305-8505, Japan
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- Ishioka Noriaki
- Japan Aerospace Exploration Agency (JAXA), 2-1-1 Sengen, Tsukuba, Ibaraki 305-8505, Japan
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- Suzuki Hiromi
- Japan Space Forum, 2-2-1 Ohtemachi, Chiyoda-ku, Tokyo 104-0004, Japan
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- Shimazu Toru
- Japan Space Forum, 2-2-1 Ohtemachi, Chiyoda-ku, Tokyo 104-0004, Japan
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- Maita Ayako
- Department of Nutritional Physiology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan
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- Okumura Yuushi
- Department of Nutritional Physiology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan
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- Nikawa Takeshi
- Department of Nutritional Physiology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan
Bibliographic Information
- Other Title
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- Mission report: "Myo Lab": a JAXA cell biology experiment in "Kibo (JEM)" of the International Space Station
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Abstract
Skeletal muscle atrophy is an often-unavoidable response to a prolonged lack of muscle use or spaceflight (referred to as "unloading"), and presents a particular challenge for astronauts during spaceflight. An increased understanding of the molecular mechanisms of muscle atrophy may lead to the development of effective therapies to combat this widespread condition. In this project, we aim to elucidate the molecular mechanisms of microgravity-induced skeletal muscle atrophy, especially physiological relevance of Cbl-b ubiquitin ligase. Japanese experimental module (JEM), "Kibo", in International Space Station has been constructed until June, 2009. This enables us to perform cell culture experiment, which is an easy system to observe direct effects of microgravity on the cell, in space for a long term. This project is called "Myo Lab", which means "Laboratory for Skeletal Muscle". This decal images our dream (space shuttle) that flight beyond Earth forward to "Kibo". In addition, the flame from shuttle means skeletal muscle.
Journal
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- Biological Sciences in Space
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Biological Sciences in Space 23 (4), 189-193, 2009
Japanese Society for Biological Sciences in Space
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Details 詳細情報について
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- CRID
- 1390282679408319360
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- NII Article ID
- 130004450606
- 10026386225
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- NII Book ID
- AN10164806
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- ISSN
- 1349967X
- 09149201
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- NDL BIB ID
- 10669956
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed