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- Terato Hiroaki
- Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, hterato@hiroshima-u.ac.jp
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- Ide Hiroshi
- Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima
書誌事項
- タイトル別名
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- Clustered DNA damage induced by heavy ion particles
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説明
Clustered DNA damage (locally multiply damaged site) is thought to be a critical lesion caused by ionizing radiation, and high LET radiation such as heavy ion particles is believed to produce high yields of such damage. Since heavy ion particles are major components of ionizing radiation in a space environment, it is important to clarify the chemical nature and biological consequences of clustered DNA damage and its relationship to the health effects of exposure to high LET particles in humans. The concept of clustered DNA damage emerged around 1980, but only recently has become the subject of experimental studies. In this article, we review methods used to detect clustered DNA damage, and the current status of our understanding of the chemical nature and repair of clustered DNA damage.
収録刊行物
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- Biological Sciences in Space
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Biological Sciences in Space 18 (4), 206-215, 2004
日本宇宙生物科学会
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詳細情報 詳細情報について
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- CRID
- 1390282679408618880
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- NII論文ID
- 130004450529
- 10014460876
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- NII書誌ID
- AN10164806
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- COI
- 1:STN:280:DC%2BD2M3ksFKksQ%3D%3D
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- ISSN
- 1349967X
- 09149201
- http://id.crossref.org/issn/1349967X
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- NDL書誌ID
- 7289132
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- PubMed
- 15858387
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- NDLサーチ
- Crossref
- PubMed
- CiNii Articles
- OpenAIRE
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- 抄録ライセンスフラグ
- 使用不可