Two-year Clinical Outcomes Post Implantation of Epic<sup>TM</sup> Self-Expanding Nitinol Stents for the Aortoiliac Occlusive Disease in Patients with Peripheral Arterial Disease
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- Tsujimura Takuya
- Kansai Rosai Hospital Cardiovascular Center
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- Iida Osamu
- Kansai Rosai Hospital Cardiovascular Center
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- Fujita Masashi
- Kansai Rosai Hospital Cardiovascular Center
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- Masuda Masaharu
- Kansai Rosai Hospital Cardiovascular Center
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- Okamoto Shin
- Kansai Rosai Hospital Cardiovascular Center
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- Ishihara Takayuki
- Kansai Rosai Hospital Cardiovascular Center
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- Nanto Kiyonori
- Kansai Rosai Hospital Cardiovascular Center
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- Kanda Takashi
- Kansai Rosai Hospital Cardiovascular Center
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- Okuno Shota
- Kansai Rosai Hospital Cardiovascular Center
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- Matsuda Yasuhiro
- Kansai Rosai Hospital Cardiovascular Center
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- Fujihara Masahiko
- Department of Cardiology, Kishiwada Tokushukai Hospital
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- Yokoi Yoshiaki
- Department of Cardiology, Kishiwada Tokushukai Hospital
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- Mano Toshiaki
- Kansai Rosai Hospital Cardiovascular Center
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説明
<p>Aim: We investigated 2-year clinical outcomes after implantaton of EpicTM self-expanding nitinol stents for patients with peripheral artery disease (PAD) due to the aortoiliac occlusive disease (AIOD).</p><p>Methods: This study was a multicenter and retrospective study. From February 2013 through October 2014, 292 lesions (chronic total occlusion, 21%; TASC Ⅱ C/D, 35%) in 217 consecutive patients (74±8 years; male, 81%; diabetes mellitus, 47%; dialysis, 21%; critical limb ischemia, 29%) who had undergone endovascular therapy (EVT) with EpicTM self-expanding nitinol stents for PAD with AIOD were analyzed. The primary endpoints were 2-year primary patency and target lesion revascularization (TLR)-free rate. The primary patency and freedom from TLR were determined by Kaplan-Meier analysis. Additionally, predictors for loss of patency were estimated by Cox proportional hazard model.</p><p>Results: The mean follow-up duration was 19.1±8.5 months. Primary patency was 87.3% at 2 years. Freedom from TLR rate was 94.1% at 2 years. Multivariate analysis revealed that the presence of diabetes mellitus was associated with a loss of patency.</p><p>Conclusion: The EpicTM self-expanding nitinol stent was demonstrated to be safe and effectivene for AIOD when tested for two years in patients with PAD.</p>
収録刊行物
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- Journal of Atherosclerosis and Thrombosis
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Journal of Atherosclerosis and Thrombosis 25 (4), 344-349, 2018
一般社団法人 日本動脈硬化学会