Progression of Non-Culprit Coronary Artery Atherosclerosis After Acute Myocardial Infarction in Comparison with Stable Angina Pectoris
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- Okayama Satoshi
- First Department of Internal Medicine, Nara Medical University.
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- Uemura Shiro
- First Department of Internal Medicine, Nara Medical University.
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- Nishida Taku
- First Department of Internal Medicine, Nara Medical University.
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- Morikawa Yoshinobu
- First Department of Internal Medicine, Nara Medical University.
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- Onoue Kenji
- First Department of Internal Medicine, Nara Medical University.
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- Takemoto Yasuhiro
- First Department of Internal Medicine, Nara Medical University.
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- Soeda Tsunenari
- First Department of Internal Medicine, Nara Medical University.
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- Somekawa Satoshi
- First Department of Internal Medicine, Nara Medical University.
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- Ishigami Ken-ichi
- First Department of Internal Medicine, Nara Medical University.
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- Takeda Yukiji
- First Department of Internal Medicine, Nara Medical University.
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- Horii Manabu
- First Department of Internal Medicine, Nara Medical University.
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- Kawata Hiroyuki
- First Department of Internal Medicine, Nara Medical University.
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- Takaoka Minoru
- First Department of Internal Medicine, Nara Medical University.
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- Nakajima Tamio
- First Department of Internal Medicine, Nara Medical University.
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- Saito Yoshihiko
- First Department of Internal Medicine, Nara Medical University.
書誌事項
- 公開日
- 2008
- DOI
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- 10.5551/jat.e539
- 公開者
- 一般社団法人 日本動脈硬化学会
この論文をさがす
説明
Aim: We previously found, using a mouse model, that activation of proinflammatory cytokines after acute myocardial infarction (AMI) augments neointimal hyperplasia of a remote artery. The present study assessed the progression of luminal narrowing of non-culprit coronary arteries (NCCA) in patients following AMI.<BR>Methods: The study group comprised 21 AMI patients successfully treated with bare-metal stents and 16 stable angina (SA) patients treated with sirolimus-eluting stents. Clinical backgrounds were similar for both groups. Quantitative coronary angiography was performed before and after stent implantation and at 6-months of follow-up.<BR>Results: We evaluated 126 non-culprit coronary segments (73 in AMI and 53 in SA). The minimum lumen diameter (MLD) (mm) of NCCA decreased significantly from 2.61±0.79 to 2.44±0.71 in the AMI group, but changed only slightly from 2.02±0.56 to 2.02±0.50 in the SA group. The absolute change in the MLD of NCCA was significantly greater (0.17±0.53) in the AMI, than in the SA (0.0070±0.261) group.<BR>Conclusion: luminal narrowing of non-culprit coronary segments progressed in AMI patients within 6 months of stent implantation, but progressed only slightly in SA patients.
収録刊行物
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- Ｊｏｕｒｎａｌ ｏｆ Ａｔｈｅｒｏｓｃｌｅｒｏｓｉｓ ａｎｄ Ｔｈｒｏｍｂｏｓｉｓ
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Ｊｏｕｒｎａｌ ｏｆ Ａｔｈｅｒｏｓｃｌｅｒｏｓｉｓ ａｎｄ Ｔｈｒｏｍｂｏｓｉｓ 15 (5), 228-234, 2008
一般社団法人 日本動脈硬化学会
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詳細情報 詳細情報について
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- CRID
- 1390282679409672960
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- NII論文ID
- 10024363253
- 130004444243
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- NII書誌ID
- AA11018976
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- DOI
- 10.5551/jat.e539
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- ISSN
- 18803873
- 13403478
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- PubMed
- 18981647
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
- OpenAIRE
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- 使用不可