Blood Vessel Wall Biomechanics and Smooth Muscle Cells

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  • 血管壁のバイオメカニクスと平滑筋細胞
  • ケッカンヘキ ノ バイオメカニクス ト ヘイカツキン サイボウ

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Abstract

Mechanical properties of blood vessel walls are characterized by the terms like large deformation, strong nonlinearity, viscoelasticity, incompressibility, and anisotropy. The methods to study the mechanical properties of a material with such complicated characteristics is described first along with its structure. An example of stress/strain analysis of blood vessel wall considering residual stress/strain is introduced. Then, effects of smooth muscle contraction and relaxation on the mechanical properties of blood vessel wall are reviewed briefly with the methods to determine the smooth muscle contractility. Finally, a novel biomechanical role of vascular smooth muscle contraction and relaxation, i.e., control of intramural strain distribution, is proposed.

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