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Procalcitonin evaluation in the diagnosis of bacteremia: a retrospective observational study
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- Hatano Toshiyuki
- Department of Emergency & Critical Care Medicine, Nagoya University Graduate School of Medicine
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- Matsuda Naoyuki
- Department of Emergency & Critical Care Medicine, Nagoya University Graduate School of Medicine
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- Iguchi Mitsutaka
- Department of Infectious Diseases, Nagoya University Hospital
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- Yagi Tetsuya
- Department of Infectious Diseases, Nagoya University Hospital
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- Ejima Tadashi
- Department of Emergency & Critical Care Medicine, Nagoya University Graduate School of Medicine
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- U. Adachi Yushi
- Department of Emergency & Critical Care Medicine, Nagoya University Graduate School of Medicine
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- Numaguchi Atsushi
- Department of Emergency & Critical Care Medicine, Nagoya University Graduate School of Medicine
Bibliographic Information
- Other Title
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- 菌血症診断におけるプロカルシトニンの有効性の検討
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Description
Objectives: To evaluate the usefulness of procalcitonin (PCT) in differential diagnosis for bacteremia or blood culture contamination and predicting either Gram-positive or Gram-negative bacteremia. Methods: We retrospectively reviewed a total of 132 cases in which PCT and C-reactive protein (CRP) were examined and blood cultures were found to be positive from November 2012 to June 2013. Results: The PCT concentrations were significantly higher in bacteremia cases (n=102) than in contamination cases (n=30) (median: 2.8 ng/ml vs. 0.3 ng/ml, P<0.001). The receiver operating characteristics-areas under the curve (ROC-AUCs) of PCT and CRP for discriminating bacteremia from contamination were 0.76 and 0.64, respectively. PCT concentrations of Gram-positive cases (n=48) were not significantly different from those of Gram-negative cases (n=54) (median: 2.1 ng/ml vs. 3.7 ng/ml, P=0.123). Conclusions: Compared with CRP, PCT could be useful in the differential diagnosis between bacteremia and contamination. However, we may not estimate either Gram-positive or Gram-negative bacteremia using CRP and PCT.
Journal
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- Journal of the Japanese Society of Intensive Care Medicine
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Journal of the Japanese Society of Intensive Care Medicine 24 (2), 115-120, 2017
The Japanese Society of Intensive Care Medicine
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Details 詳細情報について
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- CRID
- 1390282679421036160
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- NII Article ID
- 130005440078
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- ISSN
- 1882966X
- 13407988
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
- OpenAIRE
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- Abstract License Flag
- Disallowed