Case report of a patient with benign subdural extramedullary tumor treated with combined administration of gabapentin and duloxetine

KAGEYAMA Megumi, HAMAGUCHI Shinsuke, MATSUZAWA Rie, HIGASHI Naoko, IKEDA Tomohito, YAMAGUCHI Shigeki

doi:10.11321/jjspc.12-0035

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ガバペンチンとデュロキセチンの併用が有効であった硬膜内髄外腫瘍症例の治療経験
ガバペンチントデュロキセチンノヘイヨウガユウコウデアッタコウマクナイズイガイシュヨウショウレイノチリョウケイケン

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Abstract

A 42-year-old male had continuous pain in his back, hip, and bilateral lower extremities. A lumbar MRI showed a small subdural extramedullary tumor behind the L3 vertebral body. However, removal of the tumor was not adopted because the doctors determined that it was not the cause of his neurological findings. Before his visit to our outpatient service, he had been treated with various antidepressants, anticonvulsants, and analgesics, including opioid alone or in combination. However, previous treatments were ineffective. We diagnosed his pain as neuropathic and prescribed a combined 400 mg of gabapentin and 60 mg of duloxetine a day after confirmation of his past medication history. Four weeks after daily administration of these drugs, his pain had decreased to 5/10, from 10/10, determined by use of a pain scale. We concluded that the combined administration of various adjuvant analgesics can be useful for neuropathic pain relief when analgesic administration with no combined administration was ineffective treatment for intractable pain.

Journal

Journal of Japan Society of Pain Clinicians

Journal of Japan Society of Pain Clinicians 20 (1), 56-59, 2013

Japan Society of Pain Clinicians

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